Multifocal osteosarcoma
نویسندگان
چکیده
Osteosarcomatosis (also known as multifocal osteosarcoma or multiple sclerotic osteosarcoma) describes a condition in which there are multiple intraosseous foci of osteosarcoma at the time of presentation. Previous investigators have considered osteosarcomatosis to represent multicentric primary neoplasia. More recently it has been suggested that all cases of osteosarcomatosis represent rapidly progressive metastatic disease.
منابع مشابه
Synchronous multifocal osteosarcoma: results in twelve patients treated with neoadjuvant chemotherapy and simultaneous resection of all involved bones.
BACKGROUND Multifocal osteosarcoma is a rare type of tumor which is always excluded from therapy trials and is therefore rarely investigated for prognosis and treatment. PATIENTS AND METHODS Twelve patients with synchronous multifocal osteosarcoma underwent neoadjuvant chemotherapy and, when feasible, simultaneous resection of involved bones. RESULTS Four patients were unsuitable for resect...
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Background. Multifocal osteosarcoma is usually described as the occurrence of the tumour at two or more sites in a patient without pulmonary metastases and may be synchronous or metachronous. Case report. A previously well 21-year old male, who presented with a swollen, painful right knee with no history of trauma, was found to have a high-grade osteosarcoma of the distal tibia and proximal fem...
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© 2007 Associaiton médicale canadienne A white man presented with left knee pain and radiographs (Fig. 1). Open biopsy revealed highgrade osteogenic sarcoma. Bone scan showed another lesion involving the pedicle and transverse process of L1 (Fig. 2). CT and MRI were suggestive of osteosarcoma (Fig. 3). Biopsy revealed multicentric osteosarcoma. After preoperative multidrug chemotherapy, the pat...
متن کاملTreatment and prognosis for synchronous multifocal osteosarcoma in 42 patients.
Between 1986 and 2002, 42 patients with synchronous multifocal osteosarcoma were treated with two different protocols of neoadjuvant chemotherapy. When feasible, the primary and secondary tumours were excised as a combined procedure. After initial chemotherapy 26 patients were excluded from simultaneous excision of all their secondary bone lesions as their disease was too advanced. In 12 patien...
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Osteosarcoma of the skull is a very rare condition. Moreover, it is extremely rare for osteosarcoma to present as multiple lesions confined to the skull. A 58-year-old woman was admitted with two masses in the parietal area of the skull, accompanied by mild headache and tenderness. Imaging revealed two masses with a heterogeneous consistency in the cranial bones. Excision craniectomy was perfor...
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